exRNAdisease

Entry Detail

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General Information

Database ID: exR0428759 RNA Name: ACBD4 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 45132600 End Site(bp): 45144181 External Links: ENSG00000181513

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ANP32A chr15 68778535 68820897 - BSG chr19 571277 583493 + CCDC6 chr10 59788747 59906556 - CDON chr11 125955796 126063335 - DYNLL2 chr17 58083419 58095542 + EIF3C chr16 28688558 28735730 + ENO1 chr1 8861000 8879190 - GAPDH chr12 6534512 6538374 + GATAD1 chr7 92447482 92460075 + HPN chr19 35040506 35066571 + KAT7 chr17 49788681 49835026 + LIN28A chr1 26410817 26429728 + LRP4 chr11 46856717 46918642 - MAD2L2 chr1 11674480 11691650 - PDE4D chr5 58969038 60522120 - PDHB chr3 58427630 58433857 - PPP6R1 chr19 55229779 55259017 - SCAND1 chr20 35953617 35959472 - TMA16 chr4 163494442 163520539 + TPM3 chr1 154155304 154194648 - TPRN chr9 137191617 137204193 - TSR1 chr17 2322396 2336657 - TUBA1B chr12 49127782 49131397 - USP39 chr2 85602856 85649283 + VPS26C chr21 37223420 37267919 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC027290.2 chr12 122865335 122867021 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.