exRNAdisease

Entry Detail

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General Information

Database ID: exR0428760 RNA Name: ACBD5 RNA Type: mRNA Chromosome: chr10 Starnd: - Coordinate: Start Site(bp): 27195214 End Site(bp): 27242130 External Links: ENSG00000107897

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand CDC42SE1 chr1 151050971 151070325 - MAML3 chr4 139716753 140154184 - TUBA1C chr12 49188736 49274603 + RPL13A chr19 49487554 49492308 + MAP4K2 chr11 64784918 64803241 - PTCD1 chr7 99416739 99466163 - ATP5MF-PTCD1 chr7 99419749 99466197 - HSPA8 chr11 123057489 123063230 - GGA2 chr16 23463542 23521995 - TUBA1A chr12 49184795 49189080 - TMEM216 chr11 61392360 61398863 + YLPM1 chr14 74763316 74859435 + AMOT chrX 112774503 112840815 - IGF2 chr11 2129112 2141238 - PLS1 chr3 142596393 142713664 + DECR2 chr16 401858 412487 + TPI1 chr12 6867119 6870948 + RNF7 chr3 141738249 141747560 + ENO1 chr1 8861000 8879190 - RTN3 chr11 63681446 63759891 + MYL12B chr18 3261479 3278431 + B2M chr15 44711487 44718877 + LRIG2 chr1 113073198 113132260 + CKAP5 chr11 46743048 46846308 - RPS24 chr10 78033760 78056813 + GOT2 chr16 58707131 58734342 - HIPK3 chr11 33256672 33357023 + FTL chr19 48965309 48966879 + LCP1 chr13 46125920 46211871 - NACA2 chr17 61590421 61591219 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-93-5p chr7 100093815 100093837 - hsa-miR-145-5p chr5 149430661 149430683 + hsa-miR-526b-5p chr19 53694406 53694428 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020916.1 chr19 13823880 13842928 - AC132217.1 chr11 2129121 2129964 - SNHG1 chr11 62851984 62855953 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.