exRNAdisease

Entry Detail

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General Information

Database ID: exR0428761 RNA Name: ACBD6 RNA Type: mRNA Chromosome: chr1 Starnd: - Coordinate: Start Site(bp): 180269653 End Site(bp): 180502954 External Links: ENSG00000230124

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand TMEM187 chrX 153972754 153983194 + SIGMAR1 chr9 34634722 34637809 - COPS7A chr12 6724014 6731875 + SPTLC3 chr20 13008972 13169103 + BLOC1S1 chr12 55716037 55720087 + TOB2 chr22 41433494 41446801 - ACAP3 chr1 1292390 1309609 - AC011455.2 chr19 38915404 38949855 - TUBA1A chr12 49184795 49189080 - GLTP chr12 109850945 109880541 - FBXO17 chr19 38941401 38975742 - CMTM4 chr16 66614750 66696707 - AC055811.2 chr17 17202649 17237185 - PHACTR4 chr1 28369582 28500364 + NUDT15 chr13 48037726 48047221 + ADGRL1 chr19 14147743 14206187 - RER1 chr1 2391775 2405442 + EIF4H chr7 74174245 74197101 + MAFK chr7 1530702 1543043 + PLXNA3 chrX 154458281 154477779 + TOMM40 chr19 44890569 44903689 + HAUS1 chr18 46104378 46128333 + INPP5A chr10 132537787 132783480 + FTL chr19 48965309 48966879 + HINFP chr11 119121580 119136059 + MT-CO2 chrMT 7586 8269 + TUBB chr6 30720352 30725426 + SEH1L chr18 12947133 12987536 + VCP chr9 35056064 35072627 - B3GNT5 chr3 183253253 183298504 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AL121992.1 chr1 15586136 15603626 - AL121987.1 chr1 160062461 160080769 + AL645608.2 chr1 911435 914948 + MALAT1 chr11 65497688 65506516 + SLC16A1-AS1 chr1 112956415 113047055 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.