exRNAdisease

Entry Detail

---



General Information

Database ID: exR0430483 RNA Name: CALR RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 12938578 End Site(bp): 12944489 External Links: ENSG00000179218

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AARSD1 chr17 42950526 42964498 - ABCF2 chr7 151207837 151227166 - ABHD14B chr3 51968510 51983409 - ABI1 chr10 26746593 26861087 - ABRACL chr6 139028745 139043302 + AC005943.1 chr19 1578339 1605445 - AC007192.1 chr19 18153158 18178117 + AC069503.2 chr12 121888809 121921470 + AC138811.2 chr16 18788063 18801519 - ACAD8 chr11 134253495 134265855 + ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR1A chr10 102461881 102502712 - ACTR3 chr2 113890063 113962596 + ADCYAP1R1 chr7 31052461 31111479 + ADNP2 chr18 80109262 80147523 + AHCY chr20 34280268 34311802 - AK3 chr9 4709556 4742043 - AKAP8 chr19 15353385 15379798 - AKT2 chr19 40230317 40285536 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-663a chr20 26208243 26208264 - hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-6515-5p chr19 12940486 12940506 + hsa-miR-6515-3p chr19 12940521 12940540 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012236.1 chr15 31221999 31230838 - AC026362.1 chr12 122975320 122982907 + AC064802.1 chr8 114282067 114295839 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL021707.1 chr22 38739003 38749041 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.