exRNAdisease

Entry Detail

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General Information

Database ID: exR0430508 RNA Name: CANX RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 179678628 End Site(bp): 179731641 External Links: ENSG00000127022

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AACS chr12 125065434 125143333 + AAR2 chr20 36236459 36270918 + AC005837.2 chr17 76732978 76738522 + AC009133.6 chr16 29812261 29820092 + AC010463.1 chr19 17267418 17282966 + AC011511.4 chr19 10315471 10320678 - AC078927.1 chr12 66123917 66169985 - AC093323.1 chr4 6663396 6676755 + AC131160.1 chr3 183815568 183884889 - ACADVL chr17 7217125 7225266 + ACKR3 chr2 236567787 236582354 + ACOT8 chr20 45841721 45857405 - ACTG1 chr17 81509971 81523847 - ACVR2B chr3 38453890 38493142 + ADAM9 chr8 38996869 39105261 + ADAMTS1 chr21 26835755 26845409 - ADGRA3 chr4 22345071 22516066 - ADGRV1 chr5 90529344 91164437 + ADH5 chr4 99070978 99088801 - ADNP chr20 50888916 50931437 - AGO1 chr1 35869808 35930532 + AGPAT1 chr6 32168212 32178096 - AGPS chr2 177392757 177559299 + AIMP1 chr4 106315544 106349456 + AKAP10 chr17 19904302 19978343 - AKAP11 chr13 42272152 42323261 + AKAP8L chr19 15380050 15419141 - AL589666.1 chr6 85557978 85615234 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-27a-3p chr19 13836447 13836467 - hsa-miR-27b-3p chr9 95085505 95085525 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005618.1 chr5 141326210 141329357 + AC012321.1 chr16 69703065 69704652 + AC023509.1 chr12 53441741 53467528 + AC107068.1 chr4 47840122 47844339 - AC127459.1 chr16 23061406 23064173 - AL118506.1 chr20 63861212 63864293 - AL139089.1 chr13 52651305 52652279 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.