exRNAdisease

Entry Detail

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General Information

Database ID: exR0430610 RNA Name: CBX3 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 26201162 End Site(bp): 26213607 External Links: ENSG00000122565

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD17C chr15 80679684 80755621 + AC004922.1 chr7 99325879 99394653 + AC012254.2 chr18 47108188 47176345 - AC068547.1 chr2 151802651 151973949 - ACAD10 chr12 111686056 111757107 + ACTB chr7 5527148 5563784 - AD000671.2 chr19 35739252 35745432 - ADAR chr1 154582057 154628013 - ADCY1 chr7 45574140 45723116 + ADGRG2 chrX 18989307 19122637 - ADGRL2 chr1 81306160 81992436 + ADM chr11 10305073 10307397 + ADSL chr22 40346500 40390463 + AK4 chr1 65147549 65232145 + AKAP1 chr17 57085092 57121346 + AKAP9 chr7 91940867 92110673 + AKIP1 chr11 8911139 8920084 + AL021546.1 chr12 120438198 120460006 + AL022238.4 chr22 40346529 40410054 + AL139300.1 chr14 103562962 103685924 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-629-5p chr15 70079427 70079447 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011476.3 chr19 55006193 55048086 + AC016876.2 chr17 7581964 7584086 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.