exRNAdisease

Entry Detail

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General Information

Database ID: exR0437098 RNA Name: NACC1 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 13116862 End Site(bp): 13141147 External Links: ENSG00000160877

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAGAB chr15 67200667 67255195 - ABCF1 chr6 30571393 30597179 + AC005726.1 chr17 28455752 28614185 - AC011511.1 chr19 10305427 10316009 - AC099811.2 chr17 42119674 42154916 - ACACA chr17 37084992 37406836 - AEBP2 chr12 19404045 19720801 + AGAP6 chr10 49982190 50010499 + AHSA1 chr14 77457870 77469472 + AL117348.2 chr1 225886696 225924278 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-103a-3p chr5 168560904 168560926 - hsa-miR-107 chr10 89592756 89592778 - hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-331-3p chr12 95308480 95308500 + hsa-miR-324-3p chr17 7223308 7223330 - hsa-miR-346 chr10 86264747 86264769 - hsa-miR-663a chr20 26208243 26208264 - hsa-miR-671-5p chr7 151238449 151238471 + hsa-miR-361-3p chrX 85903641 85903663 - hsa-miR-362-3p chrX 50009005 50009026 + hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-1294 chr5 154347153 154347174 + hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-1307-3p chr10 103394301 103394322 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC018521.1 chr17 47945424 47981736 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.