exRNAdisease

Entry Detail

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General Information

Database ID: exR0437119 RNA Name: NAP1L1 RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 76036585 End Site(bp): 76084958 External Links: ENSG00000187109

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AGO4 chr1 35808016 35857890 + AC104109.3 chr5 134167170 134226071 - AC007040.2 chr2 70939318 70995336 - AFDN chr6 167826922 167972023 + AKR1E2 chr10 4786629 4848062 + ABHD8 chr19 17292131 17310236 - AC118549.1 chr1 77562416 77683419 - AL139353.1 chr14 31334312 31457441 - ALDH2 chr12 111766887 111817532 + ACTR3 chr2 113890063 113962596 + AIF1L chr9 131096476 131123152 + AGPAT5 chr8 6708642 6761503 + AC107871.1 chr15 68184032 68229718 - ACOT7 chr1 6264269 6394391 - ACTB chr7 5527148 5563784 - ADCY2 chr5 7396138 7830081 + AFTPH chr2 64524305 64593005 + AC007192.1 chr19 18153158 18178117 + AC008764.1 chr19 16479067 16628204 - AC120057.2 chr17 7240427 7244635 - AC139530.2 chr17 81703371 81720539 + ACKR3 chr2 236567787 236582354 + AL133352.1 chr10 100505628 100529881 - AHCYL1 chr1 109984765 110023742 + AC138811.2 chr16 18788063 18801519 - AGAP5 chr10 73674285 73698159 - ALAD chr9 113386312 113401290 - AC027796.3 chr17 3585149 3636249 - ADNP2 chr18 80109262 80147523 + AL669918.1 chr6 32813767 32838822 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007161.3 chr7 7640752 8004053 + AC007686.3 chr14 77028086 77031572 + AC020928.2 chr19 36773712 36775908 - AC022400.3 chr10 73674295 73730466 - AC022762.2 chr11 6201901 6203253 - AC084824.5 chr12 32736930 32737660 - AC116407.1 chr17 32141226 32143135 - AC125257.1 chr17 41848518 41851447 - AC144548.1 chr12 110387463 110445548 - AD000090.1 chr19 35557956 35581954 + AF131215.5 chr8 11107788 11109726 - AL022316.1 chr22 42438023 42446195 + AL121992.1 chr1 15586136 15603626 - AL133346.1 chr6 131950946 132077393 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.