exRNAdisease

Entry Detail

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General Information

Database ID: exR0437193 RNA Name: NCL RNA Type: mRNA Chromosome: chr2 Starnd: - Coordinate: Start Site(bp): 231453531 End Site(bp): 231483641 External Links: ENSG00000115053

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005258.1 chr19 2269525 2341172 + ADCYAP1R1 chr7 31052461 31111479 + AKR1B1 chr7 134442356 134459284 - AC027796.3 chr17 3585149 3636249 - AGPAT1 chr6 32168212 32178096 - AC006064.6 chr12 6556886 6607367 - AL136295.5 chr14 24147548 24166452 + ACACA chr17 37084992 37406836 - AC093525.2 chr16 2496032 2520218 + ABHD12 chr20 25294742 25390835 - ADPRH chr3 119579268 119589945 + AC018523.2 chr11 14493783 14520344 - AGPAT5 chr8 6708642 6761503 + AKAP8 chr19 15353385 15379798 - AC245033.1 chr15 82536788 82573194 - ABCD1 chrX 153724856 153744755 + ABCF1 chr6 30571393 30597179 + AFF4 chr5 132875395 132963634 - AFAP1 chr4 7758714 7939926 - AFTPH chr2 64524305 64593005 + ALDOA chr16 30064164 30070457 + AC013394.1 chr15 92883413 92949230 + ACTG1 chr17 81509971 81523847 - ADGRG6 chr6 142301854 142446266 + ACKR3 chr2 236567787 236582354 + ADAR chr1 154582057 154628013 - AC023055.1 chr12 55757275 55827546 - AHCY chr20 34280268 34311802 - AC009690.1 chr15 72284727 72375981 - ACAP1 chr17 7336529 7351477 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007780.1 chr17 68413623 68524949 + AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC023908.3 chr15 39782571 39785617 + AC026461.1 chr16 56682470 56687807 + AC064802.1 chr8 114282067 114295839 + AC092143.2 chr16 89919827 89922662 - AC106864.1 chr4 112693047 112706810 - AC245033.4 chr15 82533175 82540008 - AL034346.1 chr6 1383790 1385066 - AL137129.1 chr14 61734138 61776260 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.