exRNAdisease

Entry Detail

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General Information

Database ID: exR0437409 RNA Name: NIPSNAP1 RNA Type: mRNA Chromosome: chr22 Starnd: - Coordinate: Start Site(bp): 29554808 End Site(bp): 29581327 External Links: ENSG00000184117

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKIP1 chr11 8911139 8920084 + ACTB chr7 5527148 5563784 - AL358113.1 chr9 69035747 69255187 + ACVR1B chr12 51951699 51997078 + ACTN4 chr19 38647649 38731589 + AC006486.1 chr19 42234583 42255132 - AC092143.1 chr16 89919165 89936092 + AC009133.6 chr16 29812261 29820092 + ADH5 chr4 99070978 99088801 - AC010422.3 chr19 12643831 12648397 - AL136454.1 chr1 192716132 192716653 + AC091959.3 chr5 146203550 146339251 + AC046185.1 chr17 63702845 63752097 - AHCY chr20 34280268 34311802 - ALDH9A1 chr1 165662216 165698863 - AC048338.1 chr12 122207779 122266423 - ABT1 chr6 26596953 26600739 + ACTG1 chr17 81509971 81523847 - AC245033.1 chr15 82536788 82573194 - AC131160.1 chr3 183815568 183884889 - AFG3L2 chr18 12328944 12377227 - AL121758.1 chr20 646626 675800 - AC004922.1 chr7 99325879 99394653 + ABHD5 chr3 43690108 43734371 + AL022238.4 chr22 40346529 40410054 + AC010463.1 chr19 17267418 17282966 + AIP chr11 67483026 67491103 + AFDN chr6 167826922 167972023 + AC006064.6 chr12 6556886 6607367 - AL121594.1 chr14 35122549 35317474 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1286 chr22 20249145 20249165 - hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005899.4 chr17 32328441 32329395 + AC006160.1 chr4 17586267 17614585 - AC007952.4 chr17 19112000 19112636 - AC016026.1 chr22 17787652 17811497 - AC016876.2 chr17 7581964 7584086 - AC026362.1 chr12 122975320 122982907 + AC027031.2 chr8 106270144 106272902 + AC091820.2 chr5 167287320 167294273 - AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - AD000090.1 chr19 35557956 35581954 + AL021707.1 chr22 38739003 38749041 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.