exRNAdisease

Entry Detail

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General Information

Database ID: exR0437506 RNA Name: NOP53 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 47745546 End Site(bp): 47757058 External Links: ENSG00000105373

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC1 chr16 15949577 16143074 + ABHD3 chr18 21650901 21704780 - ABL1 chr9 130713016 130887675 + AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC118553.2 chr1 99970011 100083321 + AC124312.1 chr15 24955034 25000276 + ACACA chr17 37084992 37406836 - ACADSB chr10 123008979 123058290 + ACIN1 chr14 23058564 23095614 - ACOT8 chr20 45841721 45857405 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ACVR2B chr3 38453890 38493142 + ADAM11 chr17 44758988 44781846 + ADNP chr20 50888916 50931437 - AGPAT1 chr6 32168212 32178096 - AHCYL1 chr1 109984765 110023742 + AHR chr7 16916359 17346152 + AIP chr11 67483026 67491103 + AL121594.1 chr14 35122549 35317474 + AL136531.2 chr20 1317571 1393096 - AL355987.1 chr9 136738167 136748453 - AL928654.3 chr14 105487199 105492267 + ALDH6A1 chr14 74056847 74084492 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC021078.1 chr5 149494314 149504670 - AD000090.1 chr19 35557956 35581954 + AL132780.1 chr14 22929607 22956374 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.