exRNAdisease

Entry Detail

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General Information

Database ID: exR0437559 RNA Name: NPM1 RNA Type: mRNA Chromosome: chr5 Starnd: + Coordinate: Start Site(bp): 171387116 End Site(bp): 171411137 External Links: ENSG00000181163

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC073508.2 chr17 40627356 40665141 - AL121594.1 chr14 35122549 35317474 + AC092143.1 chr16 89919165 89936092 + AC007192.1 chr19 18153158 18178117 + ACTB chr7 5527148 5563784 - ADH5 chr4 99070978 99088801 - AC138969.1 chr16 16317444 16350590 + ABCC1 chr16 15949577 16143074 + AC008982.1 chr19 38817471 38840178 - AC004922.1 chr7 99325879 99394653 + AL365205.1 chr6 41780349 41790141 + ADD1 chr4 2843857 2930076 + AC126283.2 chr4 109713916 109801999 - AC005258.1 chr19 2269525 2341172 + AL031708.1 chr16 1632259 1686715 + AL139011.2 chr1 160216800 160285130 - ADAM23 chr2 206443532 206621127 + ABT1 chr6 26596953 26600739 + ALDH2 chr12 111766887 111817532 + AGPAT5 chr8 6708642 6761503 + ADGRG6 chr6 142301854 142446266 + AC120057.2 chr17 7240427 7244635 - ACTG1 chr17 81509971 81523847 - AHCYL1 chr1 109984765 110023742 + AACS chr12 125065434 125143333 + ADGRD1 chr12 130953907 131141469 + ALDH18A1 chr10 95605941 95656711 - ALDH3A2 chr17 19648136 19685760 + ACTR1A chr10 102461881 102502712 - AC010463.1 chr19 17267418 17282966 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC007952.4 chr17 19112000 19112636 - AC011498.1 chr19 4457962 4471493 - AC022140.1 chr5 25404733 25445925 - AD000090.1 chr19 35557956 35581954 + AL021707.1 chr22 38739003 38749041 + AL137003.1 chr6 16764346 16766883 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.