exRNAdisease

Entry Detail

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General Information

Database ID: exR0437732 RNA Name: NUP62 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 49906825 End Site(bp): 49929763 External Links: ENSG00000213024

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABRACL chr6 139028745 139043302 + AC007192.1 chr19 18153158 18178117 + AC010422.3 chr19 12643831 12648397 - AC011462.1 chr19 41350853 41425001 + AC068946.2 chr2 219209772 219222738 - AC138696.1 chr8 143247110 143276403 + ACAA2 chr18 49782164 49813953 - ACACA chr17 37084992 37406836 - ACADVL chr17 7217125 7225266 + ACAP3 chr1 1292390 1309609 - ACIN1 chr14 23058564 23095614 - ACSF3 chr16 89088375 89164121 + ACTB chr7 5527148 5563784 - ADGRE5 chr19 14380501 14408725 + ADGRL1 chr19 14147743 14206187 - AFF2 chrX 148500617 149000663 + AGAP3 chr7 151085831 151144436 + AGO3 chr1 35930718 36072500 + AKAP8L chr19 15380050 15419141 - AKT2 chr19 40230317 40285536 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002470.2 chr22 20979462 20998121 + AC004812.2 chr12 120116907 120119000 + AC073957.2 chr7 1055360 1059261 - AC091271.1 chr17 59618553 59619714 - AF131216.3 chr8 11345748 11347502 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.