exRNAdisease

Entry Detail

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General Information

Database ID: exR0437996 RNA Name: PABPC1 RNA Type: mRNA Chromosome: chr8 Starnd: - Coordinate: Start Site(bp): 100685816 End Site(bp): 100722809 External Links: ENSG00000070756

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ALDH18A1 chr10 95605941 95656711 - AC027796.3 chr17 3585149 3636249 - ACOX3 chr4 8366282 8440723 - ABHD14B chr3 51968510 51983409 - ADNP2 chr18 80109262 80147523 + AGPAT5 chr8 6708642 6761503 + AL022318.4 chr22 39014363 39033276 + ADH5 chr4 99070978 99088801 - ALDH1B1 chr9 38392702 38398661 + ACTL6A chr3 179562886 179588407 + ADCY1 chr7 45574140 45723116 + ADAR chr1 154582057 154628013 - AFDN chr6 167826922 167972023 + ABT1 chr6 26596953 26600739 + AC010422.3 chr19 12643831 12648397 - ACTG1 chr17 81509971 81523847 - AKAP9 chr7 91940867 92110673 + AC116366.3 chr5 132410832 132646079 + AC138811.2 chr16 18788063 18801519 - ACTB chr7 5527148 5563784 - AC011005.1 chr7 129126518 129130793 + ALDH9A1 chr1 165662216 165698863 - AHDC1 chr1 27534035 27604431 - AC010463.1 chr19 17267418 17282966 + ADAMTS7 chr15 78759206 78811464 - AFG1L chr6 108294991 108526796 + ADAMTSL4 chr1 150549369 150560937 + AC008982.1 chr19 38817471 38840178 - AC020909.1 chr19 50415799 50428409 + AC118549.1 chr1 77562416 77683419 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-4709-5p chr14 74480175 74480196 - hsa-miR-3620-5p chr1 228097285 228097306 + hsa-miR-7705 chr8 100703002 100703024 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007952.4 chr17 19112000 19112636 - AC010442.1 chr5 466124 473098 - AC016876.2 chr17 7581964 7584086 - AC068473.5 chr18 79677287 79679358 - AC114271.1 chr19 10333436 10336248 + AD000090.1 chr19 35557956 35581954 + AL121985.1 chr1 160670778 160699761 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.