exRNAdisease

Entry Detail

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General Information

Database ID: exR0438021 RNA Name: PAICS RNA Type: mRNA Chromosome: chr4 Starnd: + Coordinate: Start Site(bp): 56435741 End Site(bp): 56464579 External Links: ENSG00000128050

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAK1 chr2 69457997 69674349 - AAR2 chr20 36236459 36270918 + ABHD18 chr4 127965306 128039927 + AC120057.2 chr17 7240427 7244635 - AC135050.2 chr16 31083439 31094956 - AC245033.1 chr15 82536788 82573194 - ACOT7 chr1 6264269 6394391 - ACSS1 chr20 25006230 25058980 - ACTR8 chr3 53867066 53882152 - ADA2 chr22 17178790 17258235 - ADD1 chr4 2843857 2930076 + ADI1 chr2 3497366 3519531 - AEN chr15 88621337 88632281 + AGO3 chr1 35930718 36072500 + AGPAT3 chr21 43865223 43987592 + AHCYL1 chr1 109984765 110023742 + AIMP2 chr7 6009255 6023834 + AK2 chr1 33007940 33080996 - ALDH9A1 chr1 165662216 165698863 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005726.3 chr17 28573117 28574243 + AC016044.1 chr15 52800168 52805972 - AC020917.2 chr19 16440946 16443584 + AC022140.1 chr5 25404733 25445925 - AC093827.4 chr4 86924630 86936202 - AC105383.1 chr4 133075311 133149147 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.