exRNAdisease

Entry Detail

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General Information

Database ID: exR0438129 RNA Name: PCBP1 RNA Type: mRNA Chromosome: chr2 Starnd: + Coordinate: Start Site(bp): 70087477 End Site(bp): 70089203 External Links: ENSG00000169564

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABL1 chr9 130713016 130887675 + AC011448.1 chr19 19516227 19536076 + AC104581.2 chr17 7925931 7930622 - AC114490.2 chr1 34981533 35031741 - AC245033.1 chr15 82536788 82573194 - ACOT9 chrX 23701055 23766475 - ACOX3 chr4 8366282 8440723 - ACP1 chr2 264140 278283 + ACTG1 chr17 81509971 81523847 - ACTR1B chr2 97655939 97664044 - ACVR2B chr3 38453890 38493142 + ADRA2C chr4 3766348 3768526 + AHSA1 chr14 77457870 77469472 + AJM1 chr9 136844415 136848801 + AL132780.3 chr14 22946270 22982258 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC011825.3 chr18 32018829 32111779 + AC020928.2 chr19 36773712 36775908 - AC023509.1 chr12 53441741 53467528 + AC087190.3 chr16 9104848 9113181 + AC091564.7 chr11 6610883 6616594 - AL118506.1 chr20 63861212 63864293 - AL132639.2 chr14 39265703 39267061 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.