exRNAdisease

Entry Detail

---



General Information

Database ID: exR0438324 RNA Name: PEBP1 RNA Type: mRNA Chromosome: chr12 Starnd: + Coordinate: Start Site(bp): 118136124 End Site(bp): 118145584 External Links: ENSG00000089220

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABRACL chr6 139028745 139043302 + AC005258.1 chr19 2269525 2341172 + AC008982.1 chr19 38817471 38840178 - AC010422.3 chr19 12643831 12648397 - AC091167.2 chr15 90249556 90272208 + AC092143.1 chr16 89919165 89936092 + AC139530.2 chr17 81703371 81720539 + AC245033.1 chr15 82536788 82573194 - ACAD9 chr3 128879596 128916067 + ACTB chr7 5527148 5563784 - ADAM10 chr15 58588809 58749791 - ADGRG2 chrX 18989307 19122637 - ADNP2 chr18 80109262 80147523 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AKAP8L chr19 15380050 15419141 - AKR1B1 chr7 134442356 134459284 - AL133352.1 chr10 100505628 100529881 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-302d-3p chr4 112648006 112648028 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC023509.1 chr12 53441741 53467528 + AC040162.3 chr16 67882461 67886367 + AC068473.5 chr18 79677287 79679358 - AC091564.7 chr11 6610883 6616594 - AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.