exRNAdisease

Entry Detail

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General Information

Database ID: exR0438392 RNA Name: PGK1 RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 77910739 End Site(bp): 78129295 External Links: ENSG00000102144

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AIFM2 chr10 70098223 70132934 - AC012254.2 chr18 47108188 47176345 - AKIRIN2 chr6 87674860 87702233 - AHSA1 chr14 77457870 77469472 + AC011005.1 chr7 129126518 129130793 + ADPGK chr15 72751369 72785846 - AKIRIN1 chr1 38991276 39006059 + ABCC5 chr3 183919934 184017939 - ABCB7 chrX 75051048 75156732 - AFF4 chr5 132875395 132963634 - ADCY5 chr3 123282296 123449758 - AL121753.1 chr20 35267885 35280043 - AC010422.5 chr19 12664828 12669397 - AGGF1 chr5 77029251 77065234 + ACTG1 chr17 81509971 81523847 - ADGRB2 chr1 31727117 31764893 - ABCE1 chr4 145098288 145129524 + ACTR3 chr2 113890063 113962596 + AC023055.1 chr12 55757275 55827546 - AL355987.1 chr9 136738167 136748453 - ADH5 chr4 99070978 99088801 - ACAT1 chr11 108116695 108147603 + AC008581.2 chr5 77030902 77152155 + AFTPH chr2 64524305 64593005 + AAMP chr2 218264123 218270257 - ALDOA chr16 30064164 30070457 + ACTB chr7 5527148 5563784 - AL133352.1 chr10 100505628 100529881 - ALDH3A2 chr17 19648136 19685760 + AGFG1 chr2 227472152 227561214 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-29b-3p chr7 130877467 130877489 - hsa-miR-30c-5p chr6 71377003 71377025 - hsa-miR-136-5p chr14 100884716 100884738 + hsa-miR-299-3p chr14 101023832 101023853 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC000068.1 chr22 19447893 19450105 + AC007952.4 chr17 19112000 19112636 - AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC048341.2 chr12 62603909 62604399 + AC074183.1 chr7 84939349 84940245 - AC079781.5 chr7 97851688 97972985 - AC091132.5 chr17 45549781 45558738 - AC106864.1 chr4 112693047 112706810 - AC113189.4 chr17 7439506 7445966 + AC132217.1 chr11 2129121 2129964 - AC133644.3 chr2 87455476 87767359 + AL022311.1 chr22 37876148 37895563 + AL137026.2 chr10 44259602 44261813 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.