exRNAdisease

Entry Detail

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General Information

Database ID: exR0438865 RNA Name: POU5F1 RNA Type: mRNA Chromosome: chr6 Starnd: - Coordinate: Start Site(bp): 31164337 End Site(bp): 31180731 External Links: ENSG00000204531

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD4 chr14 74285269 74303055 - ABCE1 chr4 145098288 145129524 + ABHD14A-ACY1 chr3 51974706 51989183 + ABL1 chr9 130713016 130887675 + AC008764.1 chr19 16479067 16628204 - AC008982.1 chr19 38817471 38840178 - AC018512.1 chr15 43772617 43799133 - AC023055.1 chr12 55757275 55827546 - AC068946.2 chr2 219209772 219222738 - AC073508.2 chr17 40627356 40665141 - AC124312.1 chr15 24955034 25000276 + AC245033.1 chr15 82536788 82573194 - ACO2 chr22 41469117 41528989 + ACOX1 chr17 75941507 75979177 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ACTN4 chr19 38647649 38731589 + ACTR3B chr7 152759749 152855378 + ACY1 chr3 51983340 51989197 + ADAMTS7 chr15 78759206 78811464 - ADAR chr1 154582057 154628013 - AEN chr15 88621337 88632281 + AFDN chr6 167826922 167972023 + AHCY chr20 34280268 34311802 - AIMP2 chr7 6009255 6023834 + AJUBA chr14 22971177 22982551 - AKT1 chr14 104769349 104795751 - AL121758.1 chr20 646626 675800 - ALAD chr9 113386312 113401290 - ALDH1B1 chr9 38392702 38398661 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004846.1 chr14 73242651 73245979 - AC016876.2 chr17 7581964 7584086 - AC020663.1 chr16 4730115 4752565 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.