exRNAdisease

Entry Detail

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General Information

Database ID: exR0439152 RNA Name: PRRC2A RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 31620715 End Site(bp): 31637771 External Links: ENSG00000204469

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB10 chr1 229516582 229558707 - ABHD16A chr6 31686955 31703356 - ABLIM1 chr10 114431113 114768061 - AC011448.1 chr19 19516227 19536076 + AC011462.1 chr19 41350853 41425001 + AC022384.1 chr3 10249372 10285796 + AC068580.4 chr11 1734821 1763954 - AC104109.3 chr5 134167170 134226071 - AC118549.1 chr1 77562416 77683419 - ACADVL chr17 7217125 7225266 + ACAP3 chr1 1292390 1309609 - ACTG1 chr17 81509971 81523847 - ACTR3 chr2 113890063 113962596 + ADIPOR1 chr1 202940826 202958572 - ADO chr10 62804720 62808479 + AGPAT5 chr8 6708642 6761503 + AHNAK chr11 62433542 62556235 - AIG1 chr6 143060496 143341058 + AKT1 chr14 104769349 104795751 - AKT2 chr19 40230317 40285536 - AL132780.3 chr14 22946270 22982258 - AL136295.5 chr14 24147548 24166452 + AL136454.1 chr1 192716132 192716653 + ALDH9A1 chr1 165662216 165698863 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004528.1 chr19 999796 1002757 - AC007406.5 chr12 273954 277123 - AC012236.1 chr15 31221999 31230838 - AC069185.1 chr8 11797928 11802568 - AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AGAP11 chr10 86970741 87010126 + AL136982.1 chr10 86992406 87010203 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.