exRNAdisease

Entry Detail

---



General Information

Database ID: exR0439259 RNA Name: PTBP1 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 797075 End Site(bp): 812327 External Links: ENSG00000011304

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AATF chr17 36948954 37056871 + ABCF1 chr6 30571393 30597179 + ABLIM1 chr10 114431113 114768061 - AC005943.1 chr19 1578339 1605445 - AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC073508.2 chr17 40627356 40665141 - AC135050.2 chr16 31083439 31094956 - AC138811.2 chr16 18788063 18801519 - ACBD3 chr1 226144679 226186741 - ACTB chr7 5527148 5563784 - ACTG1 chr17 81509971 81523847 - ADAMTS8 chr11 130404923 130428609 - ADNP2 chr18 80109262 80147523 + AHCY chr20 34280268 34311802 - AHCYL1 chr1 109984765 110023742 + AHDC1 chr1 27534035 27604431 - AHR chr7 16916359 17346152 + AL136454.1 chr1 192716132 192716653 + AL136531.2 chr20 1317571 1393096 - ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-147a chr9 120244985 120245004 - hsa-miR-206 chr6 52144401 52144422 + hsa-miR-4523 chr17 29390668 29390688 + hsa-miR-4745-3p chr19 804977 804999 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC020928.2 chr19 36773712 36775908 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.