exRNAdisease

Entry Detail

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General Information

Database ID: exR0439498 RNA Name: RAC1 RNA Type: mRNA Chromosome: chr7 Starnd: + Coordinate: Start Site(bp): 6374527 End Site(bp): 6403967 External Links: ENSG00000136238

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002985.1 chr19 18907013 18934397 - AC005258.1 chr19 2269525 2341172 + AC093525.2 chr16 2496032 2520218 + AC107871.1 chr15 68184032 68229718 - AC124312.1 chr15 24955034 25000276 + ACOT13 chr6 24667035 24705065 + ACTB chr7 5527148 5563784 - ADAP1 chr7 897900 955407 - AL121845.2 chr20 63738270 63740398 + AL121845.3 chr20 63708864 63739103 + AL136295.1 chr14 24189157 24213473 - AL136454.1 chr1 192716132 192716653 + AL139011.2 chr1 160216800 160285130 - miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC064802.1 chr8 114282067 114295839 + AC068768.1 chr12 123262060 123262402 + AC093904.4 chr2 9106593 9109865 + AC109460.3 chr16 28974804 28990775 + AC116407.1 chr17 32141226 32143135 - AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.