exRNAdisease

Entry Detail

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General Information

Database ID: exR0440042 RNA Name: RPL10 RNA Type: mRNA Chromosome: chrX Starnd: + Coordinate: Start Site(bp): 154389955 End Site(bp): 154409168 External Links: ENSG00000147403

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCD4 chr14 74285269 74303055 - ABRACL chr6 139028745 139043302 + AC004832.3 chr22 30409255 30428990 + AC006064.6 chr12 6556886 6607367 - AC010132.3 chr7 42909273 42932174 - AC010422.3 chr19 12643831 12648397 - AC011455.2 chr19 38915404 38949855 - AC048338.1 chr12 122207779 122266423 - AC055811.2 chr17 17202649 17237185 - ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ADAL chr15 43330657 43354555 + ADAR chr1 154582057 154628013 - ADD3 chr10 109996368 110135565 + ADSL chr22 40346500 40390463 + AEN chr15 88621337 88632281 + AGBL5 chr2 27042364 27070622 + AHCY chr20 34280268 34311802 - AK2 chr1 33007940 33080996 - AKR7A2 chr1 19303965 19312146 - AL022238.4 chr22 40346529 40410054 + AL133352.1 chr10 100505628 100529881 - AL136295.5 chr14 24147548 24166452 + AL590764.2 chrX 71103987 71111575 - ALAS1 chr3 52198086 52214327 + ALDH16A1 chr19 49453225 49471050 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-6891-3p chr6 31355228 31355248 - hsa-miR-7847-3p chr11 1880105 1880125 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002550.2 chr16 19694035 19694428 - AC060766.7 chr17 35406684 35409768 - AC092490.1 chr12 8788253 8795789 + AL035446.1 chr6 140845958 140852924 - AL121992.1 chr1 15586136 15603626 - AL132780.1 chr14 22929607 22956374 + AL138828.1 chr6 135991936 136225751 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.