exRNAdisease

Entry Detail

---



General Information

Database ID: exR0440043 RNA Name: RPL10A RNA Type: mRNA Chromosome: chr6 Starnd: + Coordinate: Start Site(bp): 35468401 End Site(bp): 35470785 External Links: ENSG00000198755

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAAS chr12 53307456 53324864 - AAGAB chr15 67200667 67255195 - AAMP chr2 218264123 218270257 - ABLIM1 chr10 114431113 114768061 - AC004922.1 chr7 99325879 99394653 + AC007192.1 chr19 18153158 18178117 + AC011530.1 chr19 45779437 45785973 - AC040162.1 chr16 67929614 67936017 - AC069368.1 chr15 64841883 64930920 + AC087289.3 chr17 75898645 75930129 - AC090360.1 chr18 80034346 80097088 + AC091167.2 chr15 90249556 90272208 + AC105052.3 chr7 102637049 102671641 - AC119396.1 chr19 7348943 7383385 + ACACA chr17 37084992 37406836 - ACBD6 chr1 180269653 180502954 - ACTR2 chr2 65227753 65271253 + ADD3 chr10 109996368 110135565 + ADSL chr22 40346500 40390463 + AGBL5 chr2 27042364 27070622 + AHCYL1 chr1 109984765 110023742 + AKAP13 chr15 85380571 85749358 + AKNA chr9 114334156 114394405 - AL022238.4 chr22 40346529 40410054 + AL136454.1 chr1 192716132 192716653 + ALDOA chr16 30064164 30070457 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-7111-5p chr6 35470509 35470530 + hsa-miR-7111-3p chr6 35470558 35470579 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC012615.1 chr19 1874871 1876169 - AC020663.1 chr16 4730115 4752565 - AC023509.1 chr12 53441741 53467528 + AC063949.2 chr12 92421531 92483680 + AC067930.3 chr8 143541973 143549729 - AC126365.1 chr17 20788071 20789584 + AC132217.1 chr11 2129121 2129964 - AL022311.1 chr22 37876148 37895563 + AL110115.2 chr20 31580890 31581214 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.