exRNAdisease

General Information

Database ID:

exR0440044

RNA Name:

RPL11

RNA Type:

mRNA

Chromosome:

chr1

Starnd:

Coordinate:

Start Site(bp):

23691742

End Site(bp):

23696835

External Links:

Disease Information

Disease Name:	Pediatric TB meningitis
Disease Category:	Infections
MeSH ID:	D014390
Type:	Diseases Category/Infections
Alias:	Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Pediatric TB meningitis
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AFDN	chr6	167826922	167972023	+
AC139530.2	chr17	81703371	81720539	+
AIF1L	chr9	131096476	131123152	+
AKNA	chr9	114334156	114394405	-
AIMP2	chr7	6009255	6023834	+
ADORA2A	chr22	24417879	24442357	+
ACTG1	chr17	81509971	81523847	-
AIDA	chr1	222668013	222713210	-
ABCA3	chr16	2275881	2340746	-
ABL2	chr1	179099330	179229684	-
ACAA1	chr3	38103129	38137242	-
AKIRIN1	chr1	38991276	39006059	+
ACTR3	chr2	113890063	113962596	+
ACP1	chr2	264140	278283	+
AAAS	chr12	53307456	53324864	-
ADD2	chr2	70607618	70768225	-
AKR1B1	chr7	134442356	134459284	-
ACIN1	chr14	23058564	23095614	-
ABHD12	chr20	25294742	25390835	-
AC091167.2	chr15	90249556	90272208	+
AC245033.1	chr15	82536788	82573194	-
AC007192.1	chr19	18153158	18178117	+
ALDOA	chr16	30064164	30070457	+
ALDH4A1	chr1	18871430	18902724	-
AC010422.3	chr19	12643831	12648397	-
AC008770.2	chr19	11925075	11979290	+
ABRACL	chr6	139028745	139043302	+
ADM2	chr22	50481543	50486440	+
ADGRG1	chr16	57610652	57665580	+
ACTA1	chr1	229431245	229434098	-

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC005083.1	chr7	20217577	20221700	+
AC016876.2	chr17	7581964	7584086	-
AC040162.3	chr16	67882461	67886367	+
AC091564.7	chr11	6610883	6616594	-
AC092910.3	chr3	120094895	120136783	+
AC096992.2	chr3	136837338	136839021	-
AC104793.1	chr4	161378953	161388417	+
AC105339.2	chr15	82752884	82757208	+
AC108010.1	chr7	128574751	128626473	+
AC245014.3	chr1	145281116	145281462	+
AC245033.4	chr15	82533175	82540008	-
AL022311.1	chr22	37876148	37895563	+
AL023653.1	chrX	129794994	129796963	+
AL118516.1	chr22	46761894	46762563	-
AL133243.2	chr2	32521927	32523547	+
AL137782.1	chr13	75549773	75807120	+

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.