exRNAdisease

Entry Detail

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General Information

Database ID: exR0440047 RNA Name: RPL13A RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 49487554 End Site(bp): 49492308 External Links: ENSG00000142541

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC068580.4 chr11 1734821 1763954 - AGAP3 chr7 151085831 151144436 + ABHD17B chr9 71862452 71910931 - AC120057.2 chr17 7240427 7244635 - ADAM28 chr8 24294069 24359014 + AC124312.1 chr15 24955034 25000276 + AKT2 chr19 40230317 40285536 - ADD3 chr10 109996368 110135565 + ABL2 chr1 179099330 179229684 - ACTB chr7 5527148 5563784 - AHCY chr20 34280268 34311802 - AGBL5 chr2 27042364 27070622 + AC092143.1 chr16 89919165 89936092 + AKR7A2 chr1 19303965 19312146 - AC010422.3 chr19 12643831 12648397 - AL049779.1 chr14 67659820 67690367 - AFG3L2 chr18 12328944 12377227 - AC015813.2 chr17 57989038 58007246 - AIF1L chr9 131096476 131123152 + ACBD5 chr10 27195214 27242130 - AC004922.1 chr7 99325879 99394653 + AKT3 chr1 243488233 243851079 - AC005258.1 chr19 2269525 2341172 + AKAP8L chr19 15380050 15419141 - ALDOA chr16 30064164 30070457 + AJUBA chr14 22971177 22982551 - ACTR3 chr2 113890063 113962596 + ADPGK chr15 72751369 72785846 - AL049629.2 chr11 33698261 33722467 - ACKR3 chr2 236567787 236582354 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-3654 chr7 133034860 133034878 - hsa-miR-7704 chr2 176188843 176188861 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC004918.1 chr7 141652381 141656810 - AC007773.1 chr19 32390050 32405560 - AC007952.4 chr17 19112000 19112636 - AC009022.1 chr16 69976297 70065948 - AC010168.2 chr12 14762504 14767931 - AC011447.3 chr19 20122569 20321305 - AC020663.1 chr16 4730115 4752565 - AC021078.1 chr5 149494314 149504670 - AC023509.1 chr12 53441741 53467528 + AC051619.7 chr15 45200325 45200632 - AC067852.2 chr17 42552436 42554748 - AC068473.5 chr18 79677287 79679358 - AC104461.1 chr1 200333193 200478669 + AC105036.3 chr15 75527150 75601205 - AC132217.1 chr11 2129121 2129964 - AC139149.1 chr17 81514047 81527776 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.