exRNAdisease

General Information

Database ID:

exR0440049

RNA Name:

RPL15

RNA Type:

mRNA

Chromosome:

chr3

Starnd:

Coordinate:

Start Site(bp):

23916545

End Site(bp):

23924374

External Links:

Disease Information

Disease Name:	Pediatric TB meningitis
Disease Category:	Infections
MeSH ID:	D014390
Type:	Diseases Category/Infections
Alias:	Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID:	GSE122377
Description:	Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:	Disease Sample Source
Case Disease Type:	Pediatric TB meningitis
Case Disease SubType:	NA
Case Sample:	Pediatric TB meningitis
Control Sample:	Lumbar Puncture Cerebrospinal Fluid
Number of Case:	12
Number of Control:	12
Number of Samples:	24

Regulatory Relationship

mRNA targets:

Gene Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
ADPRHL2	chr1	36088892	36093932	+
AIF1L	chr9	131096476	131123152	+
AK2	chr1	33007940	33080996	-
AAGAB	chr15	67200667	67255195	-
AC026464.4	chr16	69299682	69322700	+
AL513165.2	chr9	37512547	37592469	-
ALDOA	chr16	30064164	30070457	+
AKR1A1	chr1	45550543	45570049	+
ABHD14B	chr3	51968510	51983409	-
ACO1	chr9	32384603	32454769	+
ACBD3	chr1	226144679	226186741	-
AKAP11	chr13	42272152	42323261	+
AC245033.1	chr15	82536788	82573194	-
ACTB	chr7	5527148	5563784	-
ADH5	chr4	99070978	99088801	-
ACADM	chr1	75724347	75787575	+
ACTR1B	chr2	97655939	97664044	-
AK4	chr1	65147549	65232145	+
AC010422.3	chr19	12643831	12648397	-
ADRM1	chr20	62302093	62308862	+
ALAS1	chr3	52198086	52214327	+
AL358113.1	chr9	69035747	69255187	+
AL022238.4	chr22	40346529	40410054	+
AHCY	chr20	34280268	34311802	-
AL713999.1	chr1	155169409	155187272	-
AC008982.1	chr19	38817471	38840178	-
ACTG2	chr2	73892314	73919865	+
AC005258.1	chr19	2269525	2341172	+
ADSL	chr22	40346500	40390463	+
ALDH9A1	chr1	165662216	165698863	-

miRNA targets:

circRNA targets:

lncRNA targets:

lncRNA Symbol	Chromosome	Start Site(bp)	End Site(bp)	Strand
AC007952.4	chr17	19112000	19112636	-
AC010642.2	chr19	58309727	58327248	-
AC012531.1	chr12	54019910	54022589	+
AC016876.2	chr17	7581964	7584086	-
AC020978.7	chr16	68224713	68227734	+
AC023509.1	chr12	53441741	53467528	+
AC024075.2	chr19	16633797	16635269	-
AC093001.1	chr3	149284782	149333653	+
AC245014.3	chr1	145281116	145281462	+
AC246817.2	chr8	2648075	2728577	-
AD000090.1	chr19	35557956	35581954	+
AL022311.1	chr22	37876148	37895563	+

Display:

Experiment Detail

GEO ID:	NA
Sample Source:	NA
Source Fraction:	NA
Platform:	NA
Method:	NA
Num of detected RNA Type:	NA
Num of detected RNAs of this Type:	NA
Sample treatment protocol:	NA
RNA Extract protocol:	NA
RNA library preparation protocol:	NA

Reference

PMID:	31434901
Title:	Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:	Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:	Nat Commun. 2019 Aug 21;10(1):3767.
Description:	Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.