exRNAdisease

Entry Detail

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General Information

Database ID: exR0440051 RNA Name: RPL18 RNA Type: mRNA Chromosome: chr19 Starnd: - Coordinate: Start Site(bp): 48615328 End Site(bp): 48619184 External Links: ENSG00000063177

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AKIRIN2 chr6 87674860 87702233 - ADAM9 chr8 38996869 39105261 + AC015813.2 chr17 57989038 58007246 - AC087289.3 chr17 75898645 75930129 - AC004922.1 chr7 99325879 99394653 + ACO2 chr22 41469117 41528989 + AIF1L chr9 131096476 131123152 + AC092143.1 chr16 89919165 89936092 + ABHD12 chr20 25294742 25390835 - ACTG1 chr17 81509971 81523847 - AGPAT1 chr6 32168212 32178096 - AEN chr15 88621337 88632281 + AACS chr12 125065434 125143333 + AL021546.1 chr12 120438198 120460006 + AL133352.1 chr10 100505628 100529881 - ADNP chr20 50888916 50931437 - ACVR1B chr12 51951699 51997078 + AC010132.3 chr7 42909273 42932174 - ACLY chr17 41866917 41930542 - AC010422.3 chr19 12643831 12648397 - ACOT2 chr14 73567620 73575658 + AC093525.2 chr16 2496032 2520218 + AHCTF1 chr1 246839098 246931967 - AC079594.2 chr3 160227454 160449829 - AC068580.4 chr11 1734821 1763954 - ALDH9A1 chr1 165662216 165698863 - ACTN4 chr19 38647649 38731589 + AGO1 chr1 35869808 35930532 + ALDH18A1 chr10 95605941 95656711 - ADM chr11 10305073 10307397 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005519.1 chr14 74289127 74294425 - AC006064.5 chr12 6510275 6510522 + AC007569.1 chr12 108628668 108642349 + AC010733.2 chr2 60925909 60931610 + AC011467.3 chr19 22603269 22608501 + AC016876.2 chr17 7581964 7584086 - AC020928.2 chr19 36773712 36775908 - AC022154.1 chr19 48619272 48624132 - AC023509.1 chr12 53441741 53467528 + AC067930.1 chr8 143579636 143580670 + AC090204.1 chr8 32927913 33045445 + AC095055.1 chr4 151139991 151141103 + AC132217.1 chr11 2129121 2129964 - AD000090.1 chr19 35557956 35581954 + AL031282.2 chr1 1702736 1737688 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.