exRNAdisease

Entry Detail

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General Information

Database ID: exR0440052 RNA Name: RPL18A RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 17859910 End Site(bp): 17864153 External Links: ENSG00000105640

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AL928654.3 chr14 105487199 105492267 + ALDOA chr16 30064164 30070457 + AC073508.2 chr17 40627356 40665141 - ADGRV1 chr5 90529344 91164437 + ACAA2 chr18 49782164 49813953 - AKT1 chr14 104769349 104795751 - AGPAT5 chr8 6708642 6761503 + ADD1 chr4 2843857 2930076 + ABCC10 chr6 43427366 43450427 + ACTB chr7 5527148 5563784 - AC010422.3 chr19 12643831 12648397 - ABHD5 chr3 43690108 43734371 + ADAM10 chr15 58588809 58749791 - ACTN4 chr19 38647649 38731589 + AASS chr7 122073549 122144255 - AGO2 chr8 140520156 140635633 - AC008982.1 chr19 38817471 38840178 - ACSF3 chr16 89088375 89164121 + AHCY chr20 34280268 34311802 - ACLY chr17 41866917 41930542 - AL359922.1 chr9 21802636 22029594 + AC104109.3 chr5 134167170 134226071 - AL358113.1 chr9 69035747 69255187 + ADAMTS10 chr19 8580240 8610735 - AC093525.2 chr16 2496032 2520218 + AC004922.1 chr7 99325879 99394653 + ABRAXAS2 chr10 124801819 124836667 + ACADVL chr17 7217125 7225266 + AL022318.4 chr22 39014363 39033276 + AC093525.1 chr16 2513965 2527955 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245297.2 chr1 149264252 149264816 + AD000090.1 chr19 35557956 35581954 + AL021154.1 chr1 23549139 23550915 - AL117378.1 chr6 131901963 131920565 + AL137782.1 chr13 75549773 75807120 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.