exRNAdisease

Entry Detail

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General Information

Database ID: exR0440053 RNA Name: RPL19 RNA Type: mRNA Chromosome: chr17 Starnd: + Coordinate: Start Site(bp): 39200283 End Site(bp): 39204732 External Links: ENSG00000108298

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand A1BG chr19 58345178 58353492 - ABCA1 chr9 104781006 104928155 - ABCC4 chr13 95019835 95301475 - ABI2 chr2 203328239 203447728 + AC018523.2 chr11 14493783 14520344 - AC073508.2 chr17 40627356 40665141 - AC084337.2 chr11 6481485 6508978 + AC134669.1 chr17 31305213 31318831 - AC245033.1 chr15 82536788 82573194 - ACACA chr17 37084992 37406836 - ACLY chr17 41866917 41930542 - ACTG1 chr17 81509971 81523847 - ADAM10 chr15 58588809 58749791 - ADGRG6 chr6 142301854 142446266 + AGO2 chr8 140520156 140635633 - AHCY chr20 34280268 34311802 - AIMP2 chr7 6009255 6023834 + AL121753.1 chr20 35267885 35280043 - AL121758.1 chr20 646626 675800 - AL138752.2 chr9 37588413 38068687 - AL513165.2 chr9 37512547 37592469 - ALDH18A1 chr10 95605941 95656711 - ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC006213.1 chr19 43996896 44003298 - AC012313.3 chr19 58346854 58362751 - AC023509.1 chr12 53441741 53467528 + AC113189.2 chr17 7420103 7444081 + AC113189.4 chr17 7439506 7445966 + AC245033.4 chr15 82533175 82540008 - AL022311.1 chr22 37876148 37895563 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.