exRNAdisease

Entry Detail

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General Information

Database ID: exR0440069 RNA Name: RPL32 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 12834485 End Site(bp): 12841582 External Links: ENSG00000144713

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCB10 chr1 229516582 229558707 - ABHD4 chr14 22598237 22613215 + AC004805.1 chr17 65538102 65641033 - AC010132.3 chr7 42909273 42932174 - AC023055.1 chr12 55757275 55827546 - AC073896.1 chr12 56285916 56316059 - AC104109.3 chr5 134167170 134226071 - ACO2 chr22 41469117 41528989 + ACTB chr7 5527148 5563784 - ACTR2 chr2 65227753 65271253 + ADAM10 chr15 58588809 58749791 - ADD3 chr10 109996368 110135565 + ADNP chr20 50888916 50931437 - AFTPH chr2 64524305 64593005 + AGO1 chr1 35869808 35930532 + AHCY chr20 34280268 34311802 - AK3 chr9 4709556 4742043 - AL645941.2 chr6 32937364 32953122 - ALCAM chr3 105366909 105576900 + ALDOA chr16 30064164 30070457 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC007218.1 chr16 9666885 9676843 - AC019294.2 chr15 75737820 75763322 + AC021078.1 chr5 149494314 149504670 - AC026362.1 chr12 122975320 122982907 + AC087190.3 chr16 9104848 9113181 + AC087280.2 chr11 6821942 6926878 - AC117386.2 chr3 150039214 150213726 + AC124068.2 chr15 89335053 89336161 + AC245014.3 chr1 145281116 145281462 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.