exRNAdisease

Entry Detail

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General Information

Database ID: exR0440135 RNA Name: RPS5 RNA Type: mRNA Chromosome: chr19 Starnd: + Coordinate: Start Site(bp): 58386400 End Site(bp): 58394806 External Links: ENSG00000083845

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AGFG2 chr7 100539203 100568220 + AL358113.1 chr9 69035747 69255187 + AKAP1 chr17 57085092 57121346 + ACO2 chr22 41469117 41528989 + AL022238.4 chr22 40346529 40410054 + AC004832.3 chr22 30409255 30428990 + AC007192.1 chr19 18153158 18178117 + AC139530.2 chr17 81703371 81720539 + AC010422.3 chr19 12643831 12648397 - AC092073.1 chr19 34396315 34409364 + AC040162.1 chr16 67929614 67936017 - ABRACL chr6 139028745 139043302 + ACTN4 chr19 38647649 38731589 + AHDC1 chr1 27534035 27604431 - AHCYL1 chr1 109984765 110023742 + AHCY chr20 34280268 34311802 - ACTR1B chr2 97655939 97664044 - ACTB chr7 5527148 5563784 - ALDOA chr16 30064164 30070457 + AK2 chr1 33007940 33080996 - AC008763.3 chr19 7678501 7682854 + AC002985.1 chr19 18907013 18934397 - AC011462.1 chr19 41350853 41425001 + ABHD10 chr3 111979010 111993368 + AC018523.2 chr11 14493783 14520344 - AC104452.1 chr3 49416777 49429314 - AHSA1 chr14 77457870 77469472 + ABCC1 chr16 15949577 16143074 + ADSL chr22 40346500 40390463 + AACS chr12 125065434 125143333 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-1244 chr2 231713368 231713393 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC026362.1 chr12 122975320 122982907 + AC091564.7 chr11 6610883 6616594 - AC121761.1 chr12 75483454 75489820 - AD000090.1 chr19 35557956 35581954 + AL121832.3 chr20 62402236 62405935 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.