exRNAdisease

Entry Detail

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General Information

Database ID: exR0443109 RNA Name: TUBB4B RNA Type: mRNA Chromosome: chr9 Starnd: + Coordinate: Start Site(bp): 137241287 End Site(bp): 137243707 External Links: ENSG00000188229

Disease Information

Disease Name: Pediatric TB meningitis Disease Category: Infections MeSH ID: D014390 Type: Diseases Category/Infections Alias: Tuberculosis, Meningeal//Meningeal Tuberculoses//Meningeal Tuberculosis//Tuberculoses, Meningeal//TB Meningitis//TB Meningitides//Tubercular Meningitis//Meningitides, Tubercular//Meningitis, Tubercular//Tubercular Meningitides//Meningitis, Tuberculous//Meningitides, Tuberculous//Tuberculous Meningitides//Tuberculous Meningitis//Tuberculosis Meningitis//Meningitides, Tuberculosis//Meningitis, Tuberculosis//Tuberculosis Meningitides//Tuberculous Hypertrophic Pachymeningitis//Hypertrophic Pachymeningitides, Tuberculous//Hypertrophic Pachymeningitis, Tuberculous//Pachymeningitides, Tuberculous Hypertrophic//Pachymeningitis, Tuberculous Hypertrophic//Tuberculous Hypertrophic Pachymeningitides

Expression Detail

GEO ID: GSE122377 Description: Tuberculous Meningitis in Pediatric Patients [CSF] Experimental Design: Disease Sample Source Case Disease Type: Pediatric TB meningitis Case Disease SubType: NA Case Sample: Pediatric TB meningitis Control Sample: Lumbar Puncture Cerebrospinal Fluid Number of Case: 12 Number of Control: 12 Number of Samples: 24

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD5 chr3 43690108 43734371 + ABLIM1 chr10 114431113 114768061 - AC004922.1 chr7 99325879 99394653 + AC008764.1 chr19 16479067 16628204 - AC011511.4 chr19 10315471 10320678 - AC068533.4 chr7 66087761 66152277 + AC092143.1 chr16 89919165 89936092 + ACBD6 chr1 180269653 180502954 - ACLY chr17 41866917 41930542 - ACSS2 chr20 34872146 34927962 + ACTR2 chr2 65227753 65271253 + ADAM10 chr15 58588809 58749791 - AEBP2 chr12 19404045 19720801 + AEN chr15 88621337 88632281 + AGO4 chr1 35808016 35857890 + AGRN chr1 1020120 1056118 + AIMP2 chr7 6009255 6023834 + AKAP7 chr6 131135467 131283535 + miRNA targets: NA circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC008105.3 chr17 45190931 45222222 - AC008738.5 chr19 33301279 33301940 + AC016355.1 chr15 67541072 67542604 - AC022075.1 chr12 10363638 10398506 + AD000090.1 chr19 35557956 35581954 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 31434901 Title: Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity Author: Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ Journal: Nat Commun. 2019 Aug 21;10(1):3767. Description: Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.