Entry Detail


General Information

Database ID:exR0445000
RNA Name:AFF3
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):99545419End Site(bp):100192428
External Links:ENSG00000144218



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC135050.2
chr16
31083439
31094956
-
ALG8
chr11
78100936
78139653
-
CCNF
chr16
2429394
2458854
+
CEP170
chr1
243124428
243255348
-
CERS5
chr12
50129289
50167533
-
FBXL19
chr16
30923055
30948783
+
FOXP2
chr7
114086327
114693772
+
GNB2
chr7
100673567
100679174
+
HDDC3
chr15
90929964
90935196
-
HMGA2
chr12
65824131
65966295
+
HS6ST1
chr2
128236716
128318868
-
INTS7
chr1
211940399
212035557
-
JRK
chr8
142657460
142681968
-
MECOM
chr3
169083499
169663775
-
NISCH
chr3
52455118
52493068
+
SIPA1L3
chr19
37907208
38208369
+
TMEM250
chr9
136114581
136118875
-
VKORC1
chr16
31090842
31095980
-
ZBED4
chr22
49853844
49890080
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-33a-5p
chr22
41900949
41900969
+
hsa-miR-520d-5p
chr19
53720111
53720130
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC026471.1
chr16
31456711
31459736
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.