Entry Detail


General Information

Database ID:exR0446600
RNA Name:CASP2
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):143288215End Site(bp):143307696
External Links:ENSG00000106144



Disease Information

Disease Name:
Disease Category:
MeSH ID:
Type:
Alias:



Expression Detail

GEO ID:GSE122377
Description:Tuberculous Meningitis in Pediatric Patients [CSF]
Experimental Design:Disease Sample Source
Case Disease Type:Pediatric TB meningitis
Case Disease SubType:NA
Case Sample:Ventricular Cerebrospinal Fluid
Control Sample:Lumbar Puncture Cerebrospinal Fluid
Number of Case:12
Number of Control:12
Number of Samples:24





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AATF
chr17
36948954
37056871
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-19a-3p
chr13
91350939
91350961
+
hsa-miR-19b-3p
chr13
91351245
91351267
+
hsa-miR-20a-5p
chr13
91351072
91351094
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-299-3p
chr14
101023832
101023853
+
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-373-3p
chr19
53788748
53788770
+
hsa-miR-20b-5p
chrX
134169850
134169872
-
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:31434901
Title:Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
Author:Rohlwink UK, Figaji A, Wilkinson KA, Horswell S, Sesay AK, Deffur A, Enslin N, Solomons R, Van Toorn R, Eley B, Levin M, Wilkinson RJ, Lai RPJ
Journal:Nat Commun. 2019 Aug 21;10(1):3767.
Description:Differential transcript expression of TBM cases are compared with healthy controls in whole blood and with non-TB cerebral infection controls in CSF.