Entry Detail


General Information

Database ID:exR0509370
RNA Name:U2AF2
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):55654146End Site(bp):55674715
External Links:ENSG00000063244



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AACS
chr12
125065434
125143333
+
ABTB1
chr3
127672935
127680926
+
AC010422.3
chr19
12643831
12648397
-
AC011448.1
chr19
19516227
19536076
+
AC027796.3
chr17
3585149
3636249
-
AC105052.1
chr7
102582523
102642869
-
AC135050.2
chr16
31083439
31094956
-
ACTB
chr7
5527148
5563784
-
ADCY3
chr2
24819169
24919839
-
ADRM1
chr20
62302093
62308862
+
AEN
chr15
88621337
88632281
+
AFG3L2
chr18
12328944
12377227
-
AHCYL1
chr1
109984765
110023742
+
AKR1B1
chr7
134442356
134459284
-
AKT2
chr19
40230317
40285536
-
AL021546.1
chr12
120438198
120460006
+
AL139011.2
chr1
160216800
160285130
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-5047
chr17
64501230
64501250
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC245014.3
chr1
145281116
145281462
+
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.