Entry Detail


General Information

Database ID:exR0510724
RNA Name:A1BG
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):58345178End Site(bp):58353492
External Links:ENSG00000121410



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTR8
chr3
53867066
53882152
-
AKT1
chr14
104769349
104795751
-
ARMC5
chr16
31458080
31467166
+
C2orf49
chr2
105337532
105349211
+
CCT7
chr2
73233420
73253021
+
CD70
chr19
6583183
6604103
-
GAPDH
chr12
6534512
6538374
+
PBX2
chr6
32184733
32190202
-
PGM1
chr1
63593411
63660245
+
PREX1
chr20
48624252
48827999
-
RNF135
chr17
30970984
30999911
+
RPL19
chr17
39200283
39204732
+
RPL37
chr5
40825262
40835222
-
SRP14
chr15
40035690
40039181
-
TMSB10
chr2
84905656
84906671
+
UNC45A
chr15
90930180
90954093
+
WDR18
chr19
984271
998438
+
WDR6
chr3
49007062
49015953
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012313.3
chr19
58346854
58362751
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.