Entry Detail


General Information

Database ID:exR0510737
RNA Name:AAGAB
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):67200667End Site(bp):67255195
External Links:ENSG00000103591



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BTBD1
chr15
83016423
83067252
-
PIMREG
chr17
6444441
6451469
+
HNRNPA1
chr12
54280193
54287088
+
SETD1A
chr16
30957754
30984664
+
RAC3
chr17
82031678
82034204
+
ARF4
chr3
57571363
57598220
-
RPL27
chr17
42998273
43002959
+
HSDL1
chr16
84122141
84145192
-
CHD7
chr8
60678740
60868028
+
CRABP2
chr1
156699606
156705816
-
DUT
chr15
48331011
48343373
+
UNC119B
chr12
120710458
120723640
+
PRDM2
chr1
13700198
13825079
+
BCAP31
chrX
153700492
153724565
-
TOMM20
chr1
235109341
235128837
-
CDPF1
chr22
46244011
46250311
-
MRPL45
chr17
38297023
38323217
+
CHMP3
chr2
86503430
86563479
-
RPS23
chr5
82273320
82278396
-
RTN4
chr2
54972187
55112621
-
CCND2
chr12
4273762
4305353
+
FUS
chr16
31180110
31194871
+
YWHAQ
chr2
9583967
9630997
-
PFN1
chr17
4945652
4949061
-
GPAM
chr10
112149865
112215377
-
HYAL2
chr3
50317790
50322782
-
R3HDM1
chr2
135531455
135725270
+
FTL
chr19
48965309
48966879
+
RPL10A
chr6
35468401
35470785
+
RIC1
chr9
5629025
5776557
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
HLA-F-AS1
chr6
29726601
29749049
-
PARD6G-AS1
chr18
80147924
80179839
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.