Entry Detail


General Information

Database ID:exR0510741
RNA Name:AARS2
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):44298731End Site(bp):44313347
External Links:ENSG00000124608



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COX5A
chr15
74919791
74938083
-
HSP90AB1
chr6
44246166
44253888
+
DENND5A
chr11
9138825
9265350
-
SFT2D3
chr2
127701497
127705242
+
USP22
chr17
20999596
21043760
-
SRSF5
chr14
69726900
69772005
+
FAM83D
chr20
38926312
38953106
+
RRP12
chr10
97356358
97426076
-
WDR27
chr6
169457212
169702067
-
KPNB1
chr17
47649476
47685505
+
RAD23A
chr19
12945855
12953642
+
RBM8A
chr1
145917714
145927678
-
TIMELESS
chr12
56416363
56449426
-
MIDN
chr19
1248553
1259140
+
MT-ND2
chrMT
4470
5511
+
GRAMD1A
chr19
34994784
35026471
+
TM9SF3
chr10
96518110
96587452
-
TP53I11
chr11
44885903
44951306
-
HSP90B1
chr12
103930107
103953645
+
NDFIP1
chr5
142108779
142154440
+
USP35
chr11
78188812
78215232
+
RPL13
chr16
89560657
89566828
+
EIF3C
chr16
28688558
28735730
+
DPPA4
chr3
109326141
109337572
-
ARSA
chr22
50622754
50628173
-
TBL1XR1
chr3
177019340
177228000
-
WDR74
chr11
62832342
62841809
-
ORAI3
chr16
30949068
30956461
+
PTOV1
chr19
49850735
49860744
+
PML
chr15
73994673
74047827
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC102953.2
chr7
1464497
1467522
-
AL355075.4
chr14
20343048
20343685
-
EBLN3P
chr9
37079645
37090928
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.