Entry Detail


General Information

Database ID:exR0510743
RNA Name:AASDH
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):56338287End Site(bp):56387508
External Links:ENSG00000157426



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CANT1
chr17
78991716
79009867
-
EMC7
chr15
34084017
34101862
-
EPN1
chr19
55675226
55709858
+
GAPDH
chr12
6534512
6538374
+
GK3P
chr4
165277812
165279679
-
GOLPH3
chr5
32124716
32174319
-
HMGCR
chr5
75336329
75362101
+
HOXB1
chr17
48528526
48531011
-
LARP6
chr15
70829130
70854157
-
MAST3
chr19
18097793
18151692
+
MGST1
chr12
16347142
16609259
+
MTHFD2
chr2
74198610
74217565
+
MTRNR2L12
chr3
96617188
96618236
-
NDUFS5
chr1
39026318
39034636
+
PIP5K1A
chr1
151197949
151249536
+
PLCXD1
chrX
276322
303356
+
RBFOX2
chr22
35738736
36028824
-
RER1
chr1
2391775
2405442
+
RPS18
chr6
33272075
33276511
+
SLC11A2
chr12
50979401
51028566
-
SPAG9
chr17
50962174
51120868
-
TFPI
chr2
187464230
187565760
-
TPP1
chr11
6612768
6619448
-
UBE2I
chr16
1308880
1327018
+
UGP2
chr2
63840940
63891562
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012485.1
chr2
238231684
238255633
+
NAALADL2-AS2
chr3
175234861
175271096
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.