Entry Detail


General Information

Database ID:exR0510744
RNA Name:AASDHPPT
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):106075501End Site(bp):106098699
External Links:ENSG00000149313



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
GTF2F2
chr13
45120510
45284893
+
CFL1
chr11
65823022
65862026
-
NUP93
chr16
56730118
56850286
+
HSD17B8
chr6
33204655
33206831
+
RPL3
chr22
39312882
39320389
-
RASSF3
chr12
64507001
64697564
+
TMBIM6
chr12
49707725
49764934
+
HNRNPL
chr19
38836388
38852347
-
CXXC4
chr4
104468308
104494901
-
PSME3
chr17
42824385
42843760
+
AHCY
chr20
34280268
34311802
-
ESRP1
chr8
94641074
94707466
+
AKAP10
chr17
19904302
19978343
-
PCLAF
chr15
64364304
64387687
-
COA3
chr17
42795147
42798704
-
MTA2
chr11
62593214
62601865
-
EIF4G2
chr11
10797050
10808940
-
WDR73
chr15
84639281
84654343
-
PUM2
chr2
20248691
20352234
-
GTPBP6
chrX
304529
318819
-
NAP1L4
chr11
2944431
2992377
-
MATR3
chr5
139273752
139331671
+
IRF7
chr11
612553
615983
-
SINHCAF
chr12
31280584
31327058
-
RAB8A
chr19
16111889
16134234
+
SPG21
chr15
64963022
64990310
-
PANK3
chr5
168548495
168579368
-
DIAPH1
chr5
141515016
141619055
-
RPS29
chr14
49570984
49599164
-
HMGA1
chr6
34236873
34246231
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC064807.1
chr8
51899268
51949874
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.