Entry Detail


General Information

Database ID:exR0510756
RNA Name:ABCA7
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):1039997End Site(bp):1065572
External Links:ENSG00000064687



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008982.1
chr19
38817471
38840178
-
AGPAT2
chr9
136673143
136687457
-
ANP32E
chr1
150218417
150236156
-
ATP2B4
chr1
203626561
203744081
+
CCNE1
chr19
29811991
29824312
+
CD99
chrX
2691187
2741309
+
EIF4G3
chr1
20806292
21176888
-
FAM50A
chrX
154444141
154450654
+
GNB1
chr1
1785285
1891117
-
HMGXB3
chr5
150000046
150053142
+
HNRNPL
chr19
38836388
38852347
-
ILF3
chr19
10654261
10692417
+
LRRK1
chr15
100919327
101078257
+
MDH2
chr7
76048051
76067508
+
METTL24
chr6
110245928
110358272
-
MPG
chr16
77007
85853
+
MT-CO1
chrMT
5904
7445
+
MTRNR2L8
chr11
10507894
10509186
-
PARP6
chr15
72241181
72272999
-
SLC29A2
chr11
66362521
66372214
-
SNX17
chr2
27370496
27377535
+
SRSF1
chr17
58000919
58007346
-
TMCO3
chr13
113491021
113554590
+
TMEM201
chr1
9588911
9614877
+
TMEM69
chr1
45688181
45694436
+
TNKS
chr8
9555912
9782346
+
TSPAN3
chr15
77041404
77083984
-
TUBA1A
chr12
49184795
49189080
-
ZNF200
chr16
3222325
3236221
-
ZNF800
chr7
127346790
127431924
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
LINC01783
chr1
16533886
16536172
-
SNHG17
chr20
38419638
38435409
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.