Entry Detail


General Information

Database ID:exR0510760
RNA Name:ABCB10
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):229516582End Site(bp):229558707
External Links:ENSG00000135776



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
PKN1
chr19
14433053
14471867
+
HELQ
chr4
83407343
83455855
-
MBOAT7
chr19
54173412
54189882
-
RPL32
chr3
12834485
12841582
-
DUSP16
chr12
12473282
12562863
-
CBX6
chr22
38861422
38872249
-
FOXK1
chr7
4682295
4771442
+
NISCH
chr3
52455118
52493068
+
MTA1
chr14
105419820
105470729
+
METTL9
chr16
21597218
21657473
+
ESPL1
chr12
53268299
53293638
+
NPHP4
chr1
5862811
5992473
-
GAREM1
chr18
32124877
32470882
-
RPS3
chr11
75399515
75422280
+
NELL2
chr12
44508275
44921848
-
VPS13D
chr1
12230030
12512047
+
BRWD1
chr21
39184176
39321559
-
PRELID1
chr5
177303799
177306949
+
NAT10
chr11
34105617
34147670
+
HTATSF1
chrX
136497079
136512346
+
GAN
chr16
81314966
81380198
+
PUS3
chr11
125893485
125903221
-
CLPTM1
chr19
44954585
44993341
+
DPP9
chr19
4675224
4724673
-
CCZ1
chr7
5898725
5926550
+
SLC37A4
chr11
119024114
119030906
-
MLEC
chr12
120687149
120701859
+
BRSK2
chr11
1389899
1462689
+
MAP4
chr3
47850690
48089272
-
PI4KB
chr1
151291797
151327715
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
SNHG4
chr5
139274102
139284899
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.