Entry Detail


General Information

Database ID:exR0510763
RNA Name:ABCB6
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):219209772End Site(bp):219218994
External Links:ENSG00000115657



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CLCN5
chrX
49922596
50099235
+
CHMP1A
chr16
89644435
89657721
-
COA1
chr7
43608456
43729717
-
PA2G4
chr12
56104537
56113910
+
PYCR2
chr1
225919877
225924340
-
HLA-E
chr6
30489509
30494194
+
SNRPD2
chr19
45687454
45692569
-
GADD45GIP1
chr19
12953119
12957223
-
VCL
chr10
73995193
74121363
+
SNRPD3
chr22
24555958
24582052
+
FARSA
chr19
12922479
12934037
-
SMDT1
chr22
42079691
42084284
+
EEF2
chr19
3976056
3985463
-
POU3F3
chr2
104853287
104858574
+
GRK2
chr11
67266473
67286556
+
GAPDH
chr12
6534512
6538374
+
WSB1
chr17
27294076
27315926
+
MYCBP2
chr13
77044657
77327094
-
SAC3D1
chr11
65040901
65044828
+
PPP4C
chr16
30075978
30085376
+
KRT7
chr12
52232520
52252186
+
AC068946.2
chr2
219209772
219222738
-
PTPRS
chr19
5158495
5340803
-
SETD1B
chr12
121804180
121832584
+
ARID1B
chr6
156776020
157210779
+
CAMK2G
chr10
73812501
73874591
-
POU6F1
chr12
51186936
51217708
-
PFN1
chr17
4945652
4949061
-
LAMP1
chr13
113297239
113323672
+
RAD51D
chr17
35092208
35121522
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.