Entry Detail


General Information

Database ID:exR0510764
RNA Name:ABCB7
RNA Type:mRNA
Chromosome:chrX
Starnd:-
Coordinate:
Start Site(bp):75051048End Site(bp):75156732
External Links:ENSG00000131269



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
YWHAZ
chr8
100916523
100953388
-
DDX5
chr17
64498254
64508199
-
MAPKAPK2
chr1
206684944
206734283
+
YWHAQ
chr2
9583967
9630997
-
MT-CO1
chrMT
5904
7445
+
CSNK2B
chr6
31665236
31670343
+
MAGED1
chrX
51803007
51902357
+
PBX2
chr6
32184733
32190202
-
CCNI
chr4
77047155
77075989
-
CFL1
chr11
65823022
65862026
-
TM7SF3
chr12
26971579
27014434
-
ADD1
chr4
2843857
2930076
+
AP002990.1
chr11
62559603
62591531
-
RARA
chr17
40309180
40357643
+
RPAIN
chr17
5419641
5432876
+
RPS12
chr6
132814569
132817564
+
IPO5
chr13
97953658
98024296
+
NOMO3
chr16
16232528
16294811
+
JMJD1C
chr10
63167221
63521850
-
MEN1
chr11
64803510
64811294
-
RAB11A
chr15
65726054
65891989
+
P4HB
chr17
81843161
81860624
-
EEF1G
chr11
62559596
62574086
-
TMSB4X
chrX
12975110
12977227
+
CAPN15
chr16
527712
554636
+
RABEP1
chr17
5282265
5386340
+
LPCAT1
chr5
1456480
1523962
-
INSIG1
chr7
155297776
155310235
+
ANP32B
chr9
97983341
98015943
+
TMED5
chr1
93149742
93180516
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
EBLN3P
chr9
37079645
37090928
+
LINC00205
chr21
45288050
45297806
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.