Entry Detail


General Information

Database ID:exR0510765
RNA Name:ABCB8
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):151028422End Site(bp):151047782
External Links:ENSG00000197150



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
USP20
chr9
129834698
129881838
+
RANBP1
chr22
20115938
20127355
+
BAG6
chr6
31639028
31652705
-
FKRP
chr19
46746046
46776988
+
SOX2
chr3
181711925
181714436
+
KPNA4
chr3
160495007
160565571
-
ATP6AP1
chrX
154428645
154436516
+
THRA
chr17
40058290
40093867
+
PTK7
chr6
43076307
43161719
+
FAM107B
chr10
14518557
14774897
-
TRMT2A
chr22
20111875
20117392
-
AC068946.2
chr2
219209772
219222738
-
YIF1B
chr19
38303558
38317273
-
FLOT1
chr6
30727709
30742732
-
HSPA1B
chr6
31827738
31830254
+
DVL3
chr3
184155377
184173614
+
EME2
chr16
1772810
1781708
+
OAZ1
chr19
2269509
2273490
+
SLC37A4
chr11
119024114
119030906
-
DDB1
chr11
61299451
61342596
-
LAMB2
chr3
49121114
49133118
-
SLC19A1
chr21
45493572
45573365
-
NKRF
chrX
119588337
119606443
-
LOXL1
chr15
73925989
73952137
+
TMBIM1
chr2
218274197
218292586
-
APBB1
chr11
6395124
6419414
-
ADNP2
chr18
80109262
80147523
+
AFF4
chr5
132875395
132963634
-
SENP3-EIF4A1
chr17
7563287
7578715
+
SMG1
chr16
18804853
18926454
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.