Entry Detail


General Information

Database ID:exR0510767
RNA Name:ABCC1
RNA Type:mRNA
Chromosome:chr16
Starnd:+
Coordinate:
Start Site(bp):15949577End Site(bp):16143074
External Links:ENSG00000103222



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TMED2
chr12
123584533
123598582
+
PCDHGB6
chr5
141408021
141512979
+
ADGRV1
chr5
90529344
91164437
+
CENPU
chr4
184694085
184734130
-
RFC5
chr12
118013588
118033130
+
BLVRB
chr19
40447765
40465764
-
MACF1
chr1
39081316
39487177
+
RPS5
chr19
58386400
58394806
+
SETD1A
chr16
30957754
30984664
+
CRTC3
chr15
90529923
90645345
+
PCDHGB1
chr5
141350102
141512979
+
PCDHGA8
chr5
141390157
141512979
+
NUCKS1
chr1
205712822
205750182
-
MT-ND4
chrMT
10760
12137
+
ASXL1
chr20
32358330
32439319
+
STRBP
chr9
123109500
123268586
-
UBE2S
chr19
55399745
55407788
-
ZDHHC4
chr7
6577434
6589374
+
NOP53
chr19
47745546
47757058
+
CD52
chr1
26317958
26320523
+
PSMB9
chr6
32844136
32859851
+
PCDHGA7
chr5
141382739
141512975
+
MT-CYB
chrMT
14747
15887
+
MT-ND5
chrMT
12337
14148
+
PCDHGA6
chr5
141373914
141512979
+
PCDHGA5
chr5
141364232
141512979
+
EIF4G2
chr11
10797050
10808940
-
MT-CO2
chrMT
7586
8269
+
SC5D
chr11
121292681
121313410
+
AC104109.3
chr5
134167170
134226071
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
AL136419.1
chr14
23969931
24051377
+
AC138932.3
chr16
14909887
14911345
-
ERVK13-1
chr16
2660348
2682379
-
GAS5
chr1
173858559
173868882
-
MIR663AHG
chr20
26167817
26251546
-
SNHG17
chr20
38419638
38435409
-
SNHG19
chr16
2154797
2155358
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.