Entry Detail


General Information

Database ID:exR0510768
RNA Name:ABCC10
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):43427366End Site(bp):43450427
External Links:ENSG00000124574



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
GTPBP1
chr22
38705742
38738299
+
PUM1
chr1
30931506
31065991
-
ELMSAN1
chr14
73715122
73790285
-
ZNF462
chr9
106863166
107013634
+
RPL13
chr16
89560657
89566828
+
DIP2A
chr21
46458891
46570015
+
YWHAG
chr7
76326799
76358991
-
DNMT1
chr19
10133345
10231286
-
ERCC2
chr19
45349837
45370918
-
EGFL7
chr9
136658856
136672678
+
MAP3K11
chr11
65597756
65615382
-
RPL18A
chr19
17859910
17864153
+
CLEC2D
chr12
9664969
9699553
+
SPATA20
chr17
50543058
50555852
+
SLC12A9
chr7
100826820
100867010
+
DYRK2
chr12
67648338
67665406
+
SF3A2
chr19
2236824
2248655
+
NCOA6
chr20
34689097
34825651
-
PLCG1
chr20
41136960
41196801
+
FBN2
chr5
128257909
128659185
-
MCCC2
chr5
71587288
71658706
+
AP5B1
chr11
65773898
65780976
-
UBAC1
chr9
135932969
135961373
-
MMADHC
chr2
149569637
149587778
-
PKMYT1
chr16
2968024
2980479
-
UGP2
chr2
63840940
63891562
+
FAM3A
chrX
154506159
154516242
-
NOTCH2
chr1
119911553
120100779
-
IMP3
chr15
75639085
75648706
-
PHGDH
chr1
119648411
119744226
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-6780b-3p
chr6
43434600
43434620
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC092139.1
chr16
81385463
81387560
+
AP001266.1
chr11
65795946
65797219
-
LINC01248
chr2
5602505
5691488
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.