Entry Detail


General Information

Database ID:exR0510773
RNA Name:ABCC4
RNA Type:mRNA
Chromosome:chr13
Starnd:-
Coordinate:
Start Site(bp):95019835End Site(bp):95301475
External Links:ENSG00000125257



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
KIF7
chr15
89608789
89655467
-
ERFE
chr2
238158970
238168900
+
POLR3D
chr8
22245133
22254601
+
SLC5A6
chr2
27199587
27212958
-
PIGC
chr1
172370189
172444086
-
AC007192.1
chr19
18153158
18178117
+
NDUFA10
chr2
239892450
240025345
-
ZBTB21
chr21
41986831
42010387
-
RUVBL1
chr3
128064778
128153914
-
ZDHHC20
chr13
21372573
21459370
-
IFI6
chr1
27666064
27672198
-
MYO1G
chr7
44962662
44979088
-
DPPA4
chr3
109326141
109337572
-
CCT8
chr21
29055805
29073797
-
BASP1
chr5
17065598
17276843
+
FNBP1
chr9
129887187
130043194
-
LTBP4
chr19
40592883
40629818
+
LARP1
chr5
154712843
154817605
+
RPL4
chr15
66498015
66524532
-
RRM1
chr11
4094707
4138932
+
SPOUT1
chr9
128819651
128829794
-
LLGL2
chr17
75525080
75575208
+
SACS
chr13
23328826
23433740
-
RPL27A
chr11
8682788
8714759
+
YIPF5
chr5
144158162
144170714
-
SRP14
chr15
40035690
40039181
-
FKBP8
chr19
18531751
18544077
-
KMT2B
chr19
35717973
35738878
+
DDX41
chr5
177511577
177516961
-
ING3
chr7
120950763
120977216
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
CRTC3-AS1
chr15
90620007
90717141
-
DLEU1
chr13
50082169
50906856
+
MALAT1
chr11
65497688
65506516
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.