Entry Detail


General Information

Database ID:exR0510777
RNA Name:ABCD1
RNA Type:mRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):153724856End Site(bp):153744755
External Links:ENSG00000101986



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ARPP19
chr15
52547045
52569883
-
BCL2L2
chr14
23298790
23311759
+
BCL2L2-PABPN1
chr14
23306835
23325369
+
HLA-A
chr6
29941260
29945884
+
HOXB4
chr17
48575507
48578350
-
MKNK2
chr19
2037465
2051244
-
MT-CO2
chrMT
7586
8269
+
NASP
chr1
45583846
45618904
+
NCL
chr2
231453531
231483641
-
PABPN1
chr14
23321289
23326185
+
TTC3
chr21
37073226
37203112
+
ZNF324B
chr19
58451611
58457833
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.